Ravindran Priyadarshini

Regulation of exocytosis during neuronal polarization

Axon specification and elongation are the most critical steps of neuron polarization. The formation of an axon requires the rapid and continuous addition of membrane material at the plasma membrane, especially at its growth cone. This is achieved by the preferential transport, tethering, and exocytosis of plasmalemmal precursor vesicles (PPVs) to the plasma membrane of the extending axon.
In this context, I am studying how exocytosis is regulated during neuronal polarization – more specifically, how the RhoGEF Arhgef7 and its downstream Rho GTPase TC10 regulate this process.
Rafael being pulled to the Badestrasse after the graduation ceremony

Rafael Krämer - first graduated PhD Student from the CRC1348 IRTG

We are happy to announce that in December 2019 Rafael Krämer from the Rumpf lab was graduated as first PhD student from the CRC1348 IRTG. Congratulations Dr. Krämer and well done!

CRC1348 Retreat 2019 Oberwerries

CRC 1348 Retreat 2019 Oberwerries

The CRC has staged a successful and productive annual retreat at the Landesturnschule Oberwerries with lots of mental and some physical exercise. We are due to return fully equipped with sweat pants, trainers and shower gel in 2020!