Hongyan Long

The three-dimensional (3D) microenvironment of cells directs cell fate and ultimately shapes tissue phenotype. Cells interact with the microenvironment through soluble chemical and biological factors, as well as biophysical cues presented by the extracellular matrix (ECM), such as ECM stiffness, and ECM tethered adhesive ligands and growth factors. While it is understood that many signaling molecules are tethered to the ECM, the soluble formats have been typically applied in biological studies. To study the role of cellular mechanotransduction events in integrin and growth factor signaling, I am developing biocompatible hydrogel systems for studying individual and synergistic effects of ECM mechanical properties and tethered growth factors on cell behavior in 3D matrices.

Rafael being pulled to the Badestrasse after the graduation ceremony

Rafael Krämer - first graduated PhD Student from the CRC1348 IRTG

We are happy to announce that in December 2019 Rafael Krämer from the Rumpf lab was graduated as first PhD student from the CRC1348 IRTG. Congratulations Dr. Krämer and well done!

CRC1348 Retreat 2019 Oberwerries

CRC 1348 Retreat 2019 Oberwerries

The CRC has staged a successful and productive annual retreat at the Landesturnschule Oberwerries with lots of mental and some physical exercise. We are due to return fully equipped with sweat pants, trainers and shower gel in 2020!