Denise Teber

VE-cadherin modifications and binding partners regulate endothelial junctions

Venous malformations are composed of enlarged and distorted vein, changes induced by increased Tie-2 signaling. But not all patients harbor a mutation in the Tie-2 gene. Identifying new mutations in genes involved in the Tie-2 pathway could help to identify new therapeutic targets.

Leukocyte extravasation is a crucial process to fight invaded pathogens. Although a lot of research has been conducted in the last years, it is still not fully understood how endothelial contacts open to allow leukocytes to leave the vascular system and fight the infection in the affected tissue.

Rafael being pulled to the Badestrasse after the graduation ceremony

Rafael Krämer - first graduated PhD Student from the CRC1348 IRTG

We are happy to announce that in December 2019 Rafael Krämer from the Rumpf lab was graduated as first PhD student from the CRC1348 IRTG. Congratulations Dr. Krämer and well done!

CRC1348 Retreat 2019 Oberwerries

CRC 1348 Retreat 2019 Oberwerries

The CRC has staged a successful and productive annual retreat at the Landesturnschule Oberwerries with lots of mental and some physical exercise. We are due to return fully equipped with sweat pants, trainers and shower gel in 2020!