Anne Aalto

Cell migration is a crucial biological process during development, homeostasis and disease. In order to migrate, cells need to polarise.  They have to form a leading edge that pushes the cell forward and a cell rear that retracts. To study cell polarisation during migration in an in vivo context, we employ zebrafish primordial germ cells (PGCs) as a model. In my project, my aim is to understand how the cells become polarised while migrating through developing tissues in the live embryo. Specifically, to identify the different structures and proteins that are polarised and the mechanism that leads to polarity. Additionally, I try to understand how the interactions with other cell types affect the polarisation of PGCs.


Rafael being pulled to the Badestrasse after the graduation ceremony

Rafael Krämer - first graduated PhD Student from the CRC1348 IRTG

We are happy to announce that in December 2019 Rafael Krämer from the Rumpf lab was graduated as first PhD student from the CRC1348 IRTG. Congratulations Dr. Krämer and well done!

CRC1348 Retreat 2019 Oberwerries

CRC 1348 Retreat 2019 Oberwerries

The CRC has staged a successful and productive annual retreat at the Landesturnschule Oberwerries with lots of mental and some physical exercise. We are due to return fully equipped with sweat pants, trainers and shower gel in 2020!