Miao Sun (Alumna since February 2021)

Neurexins regulate neurotransmission cooperating with synaptic VGCCs

Neurexins are cell adhesion molecules located at presynapse in the mammals. They play essential roles in neurotransmission and regulating synaptic strength. The function of neurexins is partially involved in the voltage-gated calcium channels, which are the critical modulators for neurotransmission and multiple signaling pathways. In my research, I use electrophysiology as the primary method; HEK cells and cultured hippocampal neurons are materials. I focus on the association between neurexins and VGCCs and how they cooperate to keep neurons working normally.