Pilot Projects

All graduate students of the CRC 1348 have the chance to apply for funding for innovative and risky projects that they develop in collaboration with other students of the CRC. This will foster interaction among students, exchange of ideas, and will guide the students into creativity and independence.

Pilot Project 1 (2019)

A technique to visualize specific cell-surface heparan sulfate proteoglycans in vivo in Drosophila melanogaster

Kristina Ehring (alumna), Henrike Ohm, Kay Grobe, Christian Klämbt
Heparan sulfate (HS) proteoglycans are dynamically expressed at the surface of virtually all cell types and act as essential regulators of growth and
(read more)

Pilot Project 2 (2019)

Exploring the interaction between tricellular occluding junctions (TCJs) and adherens junctions (AJs) and its possible role in epithelial polarization

Jone Isasti Sanchez (alumna), Yung Su Kim, Stefan Luschnig, Ivan Bedzhov
In this project, we aim to decipher the complex interactions between Adherens Junctions (AJs) and Tight Junctions (TJCs) and analyze the role of TJCs
(read more)

Pilot Project 3 (2019)

Mutations in VE-PTP: Identification of a Novel Cause of Venous Malformations in 3D-Matrices

Denise Teber (alumna), Martin Weiß, Britta Trappmann, Dietmar Vestweber
Mutations in the vascular endothelial protein tyrosine phosphatase (VE-PTP), one of the most important interaction partners of angiopoietin receptor T
(read more)

Pilot Project 4 (2019)

Tools to investigate spatiotemporal kinase signaling in epithelial and neuronal polarity

Neele Wolterhoff, Sarah Borkowsky, Sebastian Rumpf, Michael Krahn
The preliminary data our two groups (Krahn, Rumpf) allow to suggest that Par-1 activity is regulated spatially and temporally in a dynamic way. The a
(read more)

Pilot Project 5 (2020)

Biosensors to study membrane curvature stabilization during HPV16 endocytosis

Pia Brinkert (alumna), Mirsana Ebrahimkutty, Milos Galic, Mario Schelhaas
Viruses are obligatory intracellular parasites that hijack cellular mechanisms for host cell entry and replication. Therefore, they are valuable tools
(read more)

Pilot Project 6 (2020)

Identifying regulators of late endosomal cholesterol homeostasis and post-endosomal trafficking routes using proximity proteomics

Jonas Goretzko (alumnus), Anna Holthenrich (Alumna since December 2020), Ursula Rescher, Volker Gerke
Late endosomes and lysosomes control intracellular trafficking routes by monitoring the cellular homeostasis of cholesterol. Cholesterol is taken up b
(read more)

Pilot Project 7 (2022)

Optogenetic tool for manipulating cell-cell adhesion in cultured cells and in vivo

Thea Jacobs, Brice Nzigou Mombo, Seraphine Wegner, Stefan Luschnig
In multicellular organisms, cells need to form stable but reversible connections with each other to allow compartmentalization of the organisms. Cell
(read more)

Pilot Project 8 (2022)

Shedding light on inter-organellar communication: An optogenetic approach to investigate organelle contact sites

Pascal Höhne, Nivedha Veerasubramanian, Maria Bohnert, Seraphine Wegner
The group of Maria Bohnert investigates the biology of organelle contact sites, specialized structures where the membranes of different cellular organ
(read more)

Pilot Project 9 (2023)

Light-regulated protein degradation of fly Nephrin to monitor slit diaphragm dynamics in Drosophila nephrocytes

Max Gass, Nivedha Veerasubramanian, Seraphine Wegner, Michael Krahn
Many renal diseases show a severe phenotype of filtration defects in the glomeruli of the kidney. Since podocytes and the slit diaphragms they compose
(read more)

CRC 1348

Dynamic Cellular Interfaces: Formation and Function

Wiebke Bütergerds
Röntgenstraße 16
48149 D-Münster

Phone: +49 (0) 251 83 21039
SFB1348 [at] uni-muenster [dot] de

Next Seminars

Florencia Sánchez

(University of Frankfurt)

Decoding receptor signaling by ligand-free in situ confinement

06 Dec, 2023 | 11:00
Add to Calendar 2023-12-06 11:00:00 2023-12-03 03:02:12 Seminar: Florencia Sánchez Decoding receptor signaling by ligand-free in situ confinement Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Carsten Grashoff Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Rainer Friedrich

(FMI Basel)

Neuronal computations mediated by higher-order connectivity in the zebrafish brain

07 Dec, 2023 | 17:15
Add to Calendar 2023-12-07 17:15:00 2023-12-03 03:02:12 Seminar: Rainer Friedrich Neuronal computations mediated by higher-order connectivity in the zebrafish brain Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Stefan Schulte-Merker Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Marion Silies

(University of Mainz)

tba

18 Jan, 2024 | 17:15
Add to Calendar 2024-01-18 17:15:00 2023-12-03 03:02:12 Seminar: Marion Silies tba Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Christian Klämbt Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Katja Röper

(University of Cambridge)

tba

25 Jan, 2024 | 17:15
Add to Calendar 2024-01-25 17:15:00 2023-12-03 03:02:12 Seminar: Katja Röper tba Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Stefan Luschnig Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Ruben Bierings

(Erasmus Medical Center Rotterdam)

Exocytosis of Weibel-Palade bodies: how to unpack a vascular emergency kit

07 Mar, 2024 | 17:15
Add to Calendar 2024-03-07 17:15:00 2023-12-03 03:02:12 Seminar: Ruben Bierings Exocytosis of Weibel-Palade bodies: how to unpack a vascular emergency kit Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Volker Gerke Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

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