Pilot Projects

All graduate students of the CRC 1348 have the chance to apply for funding for innovative and risky projects that they develop in collaboration with other students of the CRC. This will foster interaction among students, exchange of ideas, and will guide the students into creativity and independence.

Pilot Project 1 (2019)

A technique to visualize specific cell-surface heparan sulfate proteoglycans in vivo in Drosophila melanogaster

Kristina Ehring (alumna), Henrike Ohm, Kay Grobe, Christian Klämbt
Heparan sulfate (HS) proteoglycans are dynamically expressed at the surface of virtually all cell types and act as essential regulators of growth and
(read more)

Pilot Project 2 (2019)

Exploring the interaction between tricellular occluding junctions (TCJs) and adherens junctions (AJs) and its possible role in epithelial polarization

Jone Isasti Sanchez (alumna), Yung Su Kim, Stefan Luschnig, Ivan Bedzhov
In this project, we aim to decipher the complex interactions between Adherens Junctions (AJs) and Tight Junctions (TJCs) and analyze the role of TJCs
(read more)

Pilot Project 3 (2019)

Mutations in VE-PTP: Identification of a Novel Cause of Venous Malformations in 3D-Matrices

Denise Teber (alumna), Martin Weiß, Britta Trappmann, Dietmar Vestweber
Mutations in the vascular endothelial protein tyrosine phosphatase (VE-PTP), one of the most important interaction partners of angiopoietin receptor T
(read more)

Pilot Project 4 (2019)

Tools to investigate spatiotemporal kinase signaling in epithelial and neuronal polarity

Neele Wolterhoff, Sarah Borkowsky, Sebastian Rumpf, Michael Krahn
The preliminary data our two groups (Krahn, Rumpf) allow to suggest that Par-1 activity is regulated spatially and temporally in a dynamic way. The a
(read more)

Pilot Project 5 (2020)

Biosensors to study membrane curvature stabilization during HPV16 endocytosis

Pia Brinkert (alumna), Mirsana Ebrahimkutty, Milos Galic, Mario Schelhaas
Viruses are obligatory intracellular parasites that hijack cellular mechanisms for host cell entry and replication. Therefore, they are valuable tools
(read more)

Pilot Project 6 (2020)

Identifying regulators of late endosomal cholesterol homeostasis and post-endosomal trafficking routes using proximity proteomics

Jonas Goretzko (alumnus), Anna Holthenrich (Alumna since December 2020), Ursula Rescher, Volker Gerke
Late endosomes and lysosomes control intracellular trafficking routes by monitoring the cellular homeostasis of cholesterol. Cholesterol is taken up b
(read more)

Pilot Project 7 (2022)

Optogenetic tool for manipulating cell-cell adhesion in cultured cells and in vivo

Thea Jacobs, Brice Nzigou Mombo, Seraphine Wegner, Stefan Luschnig
In multicellular organisms, cells need to form stable but reversible connections with each other to allow compartmentalization of the organisms. Cell
(read more)

Pilot Project 8 (2022)

Shedding light on inter-organellar communication: An optogenetic approach to investigate organelle contact sites

Pascal Höhne, Nivedha Veerasubramanian, Maria Bohnert, Seraphine Wegner
The group of Maria Bohnert investigates the biology of organelle contact sites, specialized structures where the membranes of different cellular organ
(read more)

Pilot Project 9 (2023)

Light-regulated protein degradation of fly Nephrin to monitor slit diaphragm dynamics in Drosophila nephrocytes

Max Gass, Nivedha Veerasubramanian, Seraphine Wegner, Michael Krahn
Many renal diseases show a severe phenotype of filtration defects in the glomeruli of the kidney. Since podocytes and the slit diaphragms they compose
(read more)

CRC 1348

Dynamic Cellular Interfaces: Formation and Function

Wiebke Bütergerds
Röntgenstraße 16
48149 D-Münster

Phone: +49 (0) 251 83 21039
SFB1348 [at] uni-muenster [dot] de

Next Seminars

Anna Huttenlocher

(University of Wisconsin–Madison)

Collective migration during homeostasis and tissue repair

28 Sep, 2023 | 17:15
Add to Calendar 2023-09-28 17:15:00 2023-09-25 05:57:42 Seminar: Anna Huttenlocher Collective migration during homeostasis and tissue repair Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Erez Raz Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Jacqui Tabler

(MPI Dresden)

Collagen organisation regulates context-dependent cellular dynamics of mesenchymal collectives in vivo

19 Oct, 2023 | 17:15
Add to Calendar 2023-10-19 17:15:00 2023-09-25 05:57:42 Seminar: Jacqui Tabler Collagen organisation regulates context-dependent cellular dynamics of mesenchymal collectives in vivo Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Phil King

(University of Michigan)

Cooperation between the EPHB4 receptor tyrosine kinase and the RASA1 Ras GTPase-activating protein (p120 RasGAP) in the development and function of the blood and lymphatic vasculatures

02 Nov, 2023 | 17:15
Add to Calendar 2023-11-02 17:15:00 2023-09-25 05:57:42 Seminar: Phil King Cooperation between the EPHB4 receptor tyrosine kinase and the RASA1 Ras GTPase-activating protein (p120 RasGAP) in the development and function of the blood and lymphatic vasculatures Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Ralf Adams Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Mirka Uhlirova

(University of Köln)

Understanding the mechanisms of multinucleated giant cell formation

09 Nov, 2023 | 17:15
Add to Calendar 2023-11-09 17:15:00 2023-09-25 05:57:42 Seminar: Mirka Uhlirova Understanding the mechanisms of multinucleated giant cell formation MUltiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Stefan Luschnig Europe/Berlin public

MUltiscale Imaging Center, Röntgenstraße 16, 48149 Münster

Michael Schrader

(University of Exeter)

Organelle Interplay ‐ Peroxisome Interactions and Dynamics in Human Health and Disease

16 Nov, 2023 | 17:15
Add to Calendar 2023-11-16 17:15:00 2023-09-25 05:57:42 Seminar: Michael Schrader Organelle Interplay ‐ Peroxisome Interactions and Dynamics in Human Health and Disease Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster SFB1348 Christos Gatsogiannis Europe/Berlin public

Multiscale Imaging Center, Röntgenstraße 16, 48149 Münster

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